Tuesday, January 11, 2011

Shingles Vaccine Looks Safe and Effective for Many Older Adults



Variation in severity of Shingles lesions

The vaccine is proving to be a safe bet for senior citizens but it isn't cheap.
Jane Adrian, 61, a landscape architect in Glendale, Calif., saw her parents and two co-workers suffer from the painful, blistering condition known as shingles, so when the vaccine became available, she got it.

Even though the vaccine is only about 55 percent effective, "it's better than nothing," she said. "Now I feel relieved."

A study of a cross-section of adults enrolled with a health-management organization in southern California shows that the vaccine provides protection for many older adults without many side effects.

The findings are published in the Jan. 12 issue of the Journal of the American Medical Association.

Shingles is caused by the herpes zoster virus and only strikes people who have had chicken pox. It usually starts as a rash on one side of the face or body, often causing pain, itching and tingling. About a million cases occur in the United States each year, and attacks can last two to four weeks.

"Even after the rash has healed, the pain can last for months or even years," said lead study author HungFu Tseng, a research scientist at the Kaiser Permanente Division of Research and Evaluation in Pasadena, Calif.

Zostavax, as the vaccine is called, was approved in 2006, based on the results of clinical trials. The U.S. Centers for Disease Control and Prevention recommends the shot for eligible people aged 60 and older.

Tseng's team wanted to test the vaccine's real-world performance, so they compared 75,761 vaccinated members of the Kaiser Permanente health plan to 227,283 members who elected not to have the shot. Kaiser funded the study.

In vaccinated individuals, the rate of shingles was 6.4 cases per 1,000 people in a year while it was twice that -- 13 per 1,000 -- in the unvaccinated population, the investigators found.

The vaccine also reduced the risk of ophthalmic herpes zoster (infection that affects the eye) by 63 percent and hospitalization by 65 percent.

Those who had been vaccinated were more likely to be white, female and in better overall health than the unvaccinated people, the researchers noted. Lack of awareness, concerns about effectiveness or safety, and cost may have kept some people from getting the shot, Tseng said.

"People 60 and over can consider talking to their physician about the possibility of receiving the vaccine to reduce their risk, and the doctor can evaluate if they are eligible," said Tseng.

Patients with leukemia, lymphoma, HIV or an allergy to any ingredients in the vaccine are ineligible for the shot.
Well, I am going to get the Shingles vaccine since my experience with chickenpox was horrible. I do not want a repeat of that experience, especially in the eye.

I'll shell out the couple of hundred dollars for the reassurance. Talk to your own physician and see what s/he recommends.